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metsign software  (MathWorks Inc)


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    Structured Review

    MathWorks Inc metsign software
    An example of spectrum deconvolution by <t>MetSign.</t> (A) XIC and background noise level estimation. The entire XIC is segmented into four peak groups because of the discontinuity of signals in the chromatographic dimension (scan). It was detected that the first segment contains at least one peak, and leaving the rest retention time range of XIC as noise area for polynomial fitting and median filtering. The estimated noise level is shown in red line. (B) Detection of significant peaks. The dominant peaks are determined by the first derivative cross zero position from positive to negative values and meeting the criteria of minimum data points in the two sides of each peak. (C) Detection of non-significant peaks (hidden peaks). The hidden peaks are recognized as the second derivative cross zero position with changing from positive to negative values and the first derivative value is negative, or changing from negative to positive values and the first derivative value is positive. There is one hidden peak that is detected in the example. (D) Two peaks deconvoluted by mixture EMG models.
    Metsign Software, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/metsign software/product/MathWorks Inc
    Average 90 stars, based on 1 article reviews
    metsign software - by Bioz Stars, 2026-04
    90/100 stars

    Images

    1) Product Images from "A Data Pre-processing Method for Liquid Chromatography Mass Spectrometry-based Metabolomics"

    Article Title: A Data Pre-processing Method for Liquid Chromatography Mass Spectrometry-based Metabolomics

    Journal: Analytical chemistry

    doi: 10.1021/ac3016856

    An example of spectrum deconvolution by MetSign. (A) XIC and background noise level estimation. The entire XIC is segmented into four peak groups because of the discontinuity of signals in the chromatographic dimension (scan). It was detected that the first segment contains at least one peak, and leaving the rest retention time range of XIC as noise area for polynomial fitting and median filtering. The estimated noise level is shown in red line. (B) Detection of significant peaks. The dominant peaks are determined by the first derivative cross zero position from positive to negative values and meeting the criteria of minimum data points in the two sides of each peak. (C) Detection of non-significant peaks (hidden peaks). The hidden peaks are recognized as the second derivative cross zero position with changing from positive to negative values and the first derivative value is negative, or changing from negative to positive values and the first derivative value is positive. There is one hidden peak that is detected in the example. (D) Two peaks deconvoluted by mixture EMG models.
    Figure Legend Snippet: An example of spectrum deconvolution by MetSign. (A) XIC and background noise level estimation. The entire XIC is segmented into four peak groups because of the discontinuity of signals in the chromatographic dimension (scan). It was detected that the first segment contains at least one peak, and leaving the rest retention time range of XIC as noise area for polynomial fitting and median filtering. The estimated noise level is shown in red line. (B) Detection of significant peaks. The dominant peaks are determined by the first derivative cross zero position from positive to negative values and meeting the criteria of minimum data points in the two sides of each peak. (C) Detection of non-significant peaks (hidden peaks). The hidden peaks are recognized as the second derivative cross zero position with changing from positive to negative values and the first derivative value is negative, or changing from negative to positive values and the first derivative value is positive. There is one hidden peak that is detected in the example. (D) Two peaks deconvoluted by mixture EMG models.

    Techniques Used:

    An example of peak picking by MetSgin and MZmine2.6. (A) Peak fitting results by MetSign using mixture EMG model. (B) Five peak components deconvoluted by peak detection and EMG fitting algorithm by MetSign. (C), (D) and (E) are the peak deconvolution results on same data by MZmine2.6. MetSign detected five peaks including four dominant peaks and one hidden peak; while MZmine2.6 correctly detected the two abundant peaks on the right and incorrectly considered the three peaks on the left as one peak.
    Figure Legend Snippet: An example of peak picking by MetSgin and MZmine2.6. (A) Peak fitting results by MetSign using mixture EMG model. (B) Five peak components deconvoluted by peak detection and EMG fitting algorithm by MetSign. (C), (D) and (E) are the peak deconvolution results on same data by MZmine2.6. MetSign detected five peaks including four dominant peaks and one hidden peak; while MZmine2.6 correctly detected the two abundant peaks on the right and incorrectly considered the three peaks on the left as one peak.

    Techniques Used:

    Comparison of alignment results among MetSign, MZmine2.6, XCMS2 with retention time correction, and XCMS2 without retention time correction. (A) εm/z ≤ 6 ppm. (B) εm/z ≤ 10 ppm. The εm/z was set as 0.025 for XCMS2 as specified by the software.
    Figure Legend Snippet: Comparison of alignment results among MetSign, MZmine2.6, XCMS2 with retention time correction, and XCMS2 without retention time correction. (A) εm/z ≤ 6 ppm. (B) εm/z ≤ 10 ppm. The εm/z was set as 0.025 for XCMS2 as specified by the software.

    Techniques Used: Software



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    metsign software  (MathWorks Inc)
    90
    MathWorks Inc metsign software
    An example of spectrum deconvolution by <t>MetSign.</t> (A) XIC and background noise level estimation. The entire XIC is segmented into four peak groups because of the discontinuity of signals in the chromatographic dimension (scan). It was detected that the first segment contains at least one peak, and leaving the rest retention time range of XIC as noise area for polynomial fitting and median filtering. The estimated noise level is shown in red line. (B) Detection of significant peaks. The dominant peaks are determined by the first derivative cross zero position from positive to negative values and meeting the criteria of minimum data points in the two sides of each peak. (C) Detection of non-significant peaks (hidden peaks). The hidden peaks are recognized as the second derivative cross zero position with changing from positive to negative values and the first derivative value is negative, or changing from negative to positive values and the first derivative value is positive. There is one hidden peak that is detected in the example. (D) Two peaks deconvoluted by mixture EMG models.
    Metsign Software, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/metsign software/product/MathWorks Inc
    Average 90 stars, based on 1 article reviews
    metsign software - by Bioz Stars, 2026-04
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    An example of spectrum deconvolution by MetSign. (A) XIC and background noise level estimation. The entire XIC is segmented into four peak groups because of the discontinuity of signals in the chromatographic dimension (scan). It was detected that the first segment contains at least one peak, and leaving the rest retention time range of XIC as noise area for polynomial fitting and median filtering. The estimated noise level is shown in red line. (B) Detection of significant peaks. The dominant peaks are determined by the first derivative cross zero position from positive to negative values and meeting the criteria of minimum data points in the two sides of each peak. (C) Detection of non-significant peaks (hidden peaks). The hidden peaks are recognized as the second derivative cross zero position with changing from positive to negative values and the first derivative value is negative, or changing from negative to positive values and the first derivative value is positive. There is one hidden peak that is detected in the example. (D) Two peaks deconvoluted by mixture EMG models.

    Journal: Analytical chemistry

    Article Title: A Data Pre-processing Method for Liquid Chromatography Mass Spectrometry-based Metabolomics

    doi: 10.1021/ac3016856

    Figure Lengend Snippet: An example of spectrum deconvolution by MetSign. (A) XIC and background noise level estimation. The entire XIC is segmented into four peak groups because of the discontinuity of signals in the chromatographic dimension (scan). It was detected that the first segment contains at least one peak, and leaving the rest retention time range of XIC as noise area for polynomial fitting and median filtering. The estimated noise level is shown in red line. (B) Detection of significant peaks. The dominant peaks are determined by the first derivative cross zero position from positive to negative values and meeting the criteria of minimum data points in the two sides of each peak. (C) Detection of non-significant peaks (hidden peaks). The hidden peaks are recognized as the second derivative cross zero position with changing from positive to negative values and the first derivative value is negative, or changing from negative to positive values and the first derivative value is positive. There is one hidden peak that is detected in the example. (D) Two peaks deconvoluted by mixture EMG models.

    Article Snippet: MetSign software was implemented using MATLAB 2010b and is free for purpose of academic research.

    Techniques:

    An example of peak picking by MetSgin and MZmine2.6. (A) Peak fitting results by MetSign using mixture EMG model. (B) Five peak components deconvoluted by peak detection and EMG fitting algorithm by MetSign. (C), (D) and (E) are the peak deconvolution results on same data by MZmine2.6. MetSign detected five peaks including four dominant peaks and one hidden peak; while MZmine2.6 correctly detected the two abundant peaks on the right and incorrectly considered the three peaks on the left as one peak.

    Journal: Analytical chemistry

    Article Title: A Data Pre-processing Method for Liquid Chromatography Mass Spectrometry-based Metabolomics

    doi: 10.1021/ac3016856

    Figure Lengend Snippet: An example of peak picking by MetSgin and MZmine2.6. (A) Peak fitting results by MetSign using mixture EMG model. (B) Five peak components deconvoluted by peak detection and EMG fitting algorithm by MetSign. (C), (D) and (E) are the peak deconvolution results on same data by MZmine2.6. MetSign detected five peaks including four dominant peaks and one hidden peak; while MZmine2.6 correctly detected the two abundant peaks on the right and incorrectly considered the three peaks on the left as one peak.

    Article Snippet: MetSign software was implemented using MATLAB 2010b and is free for purpose of academic research.

    Techniques:

    Comparison of alignment results among MetSign, MZmine2.6, XCMS2 with retention time correction, and XCMS2 without retention time correction. (A) εm/z ≤ 6 ppm. (B) εm/z ≤ 10 ppm. The εm/z was set as 0.025 for XCMS2 as specified by the software.

    Journal: Analytical chemistry

    Article Title: A Data Pre-processing Method for Liquid Chromatography Mass Spectrometry-based Metabolomics

    doi: 10.1021/ac3016856

    Figure Lengend Snippet: Comparison of alignment results among MetSign, MZmine2.6, XCMS2 with retention time correction, and XCMS2 without retention time correction. (A) εm/z ≤ 6 ppm. (B) εm/z ≤ 10 ppm. The εm/z was set as 0.025 for XCMS2 as specified by the software.

    Article Snippet: MetSign software was implemented using MATLAB 2010b and is free for purpose of academic research.

    Techniques: Software